Jurnal Kimia Unand

Isolasi Senyawa Metabolit Sekunder Dari Fraksi Aktif Antibakteri Pada Tumbuhan Sirih Merah (Piper porphyrophyllum)

Mai Efdi, M. Iqbal Alfarisyi, Bustanul Arifin — Wed, 30 Nov 2022 00:00:00 +0700

The red betel plant (Piper porphyrophyllum) belongs to the Piperaceae family which is traditionally used to treat various diseases, including headaches, bone pain, chest tightness, leprosy, stomach ache, as well as for various other diseases such as skin diseases and diabetes. In this study, the antibacterial activity was tested for the hexane, ethyl acetate and methanol extracts of red betel nut using the disc diffusion method and the isolation of secondary metabolites from the hexane fraction of red betel nut using column chromatography technique. Determination of the antibacterial activity of the three fractions showed that the methanol extract had better antibacterial activity compared to the hexane extract and ethyl acetate extract. UV spectrum analysis showed 3 bands with absorption of 282 nm in band I, 274.80 nm in band II and 224.80 nm in band III which means that they show characteristics for triterpenoid group compounds. FTIR analysis showed the presence of C-H, CH₂, C=O, C-O alcohol and geminal dimethyl functional groups in the isolated compounds.

IDENTIFIKASI METABOLIT SEKUNDER DAN UJI AKTIVITAS ANTIOKSIDAN DARI EKSTRAK DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.) Merr).

Norman Ferdinal, Lusi Seprianti, A. Afrizal — Thu, 30 Nov 2023 00:00:00 +0700

Sambung nyawa (Gynura procumbens (Lour.) Merr) is one of the plants used in traditional medicine. This has life-saving properties such as preventing polyps, dysentery, hypertension, diabetes, and cancer. In this study, the secondary metabolite content and antioxidant activity of sambung nyawa leaf extract were tested and its antioxidant activity. The extraction process was carried out by multilevel maceration using three different solvents, starting with hexane, ethyl acetate, and methanol. Secondary metabolite content test results showed that ironwood leaves contain flavonoids, phenolics, steroids, terpenoids, and alkaloids. The result of the antioxidant activity test using the DPPH method (1,1-Difenil-2- pikrilhidrazil) showed that the methanol extract showed very strong activity with an IC50 value of 15,01 mg/L, while the ethyl acetate showed moderate antioxidant activity with an IC50 value of 147,04 mg/L, and the hexane extract showed antioxidant activity with an IC50 value of 361,66 mg/L.

Optimalisasi Proses Transportasi Anilin Menggunakan Membran Minyak Nabati dalam Teknik Membran Cair

Refinel, Emil Salim, Ikhsan Gusti Rilma — Thu, 30 Nov 2023 00:00:00 +0700

Aniline transport using a supported liquid membrane technique has been carried out in the separation of aniline from aqueous solutions. The aniline transport process used vegetable oil as a liquid membrane and ceramics as a support material. The concentration aniline was determined using an UltraViolet-Visible (UV-Vis) Spectrophotometer at a wavelength of 230 nm. Optimal conditions found that a good type of liquid membrane was olive oil, a pH value of 3 in the source phase, the concentration of aniline 12 x 10^-5 M, the concentration of HCl 1.0 M, and a stirring time of 90 minutes. Under optimum conditions, the percentage of aniline in the receiving phase was 36.19% and source phase was 1.48%. HCl is not able to attract all the molecules that are in the membrane phase. The receiving compound which has a strong affinity will provide a large amount of transport for the aniline transport process.

Penggunaan ZnO/Zeolit dalam Degradasi Fenol Secara Fotolisis dan Aplikasinya Pada Limbah Karet

Z. Zilfa, Wilda Putri Suhada, Rahmiana Zein — Thu, 30 Nov 2023 00:00:00 +0700

Phenol is one of the organic compounds that are toxic and carcinogenic. In this study ZnO/zeolite was used to degrade phenol by photolysis and its application to rubber waste. Phenol analysis was performed using a UV-Vis spectrophotometer and Fourier Transform Infrared (FTIR), while the ZnO/zeolite characterization used FTIR and X-Ray Diffraction (XRD). The results showed that the percentage of phenol degradation without a catalyst was 15.79% with UV irradiation for 75 minutes and increased to 79.63% with the addition of 0.4 g ZnO/zeolite. Phenol degradation in rubber wastewater samples using ZnO/zeolite obtained a degradation percentage of 58.28%. Phenol analysis before and after degradation showed a shift in wave number which indicated the occurrence of degradation. Characterization of ZnO/zeolite before and after degradation using FTIR and XRD showed that there was no change in the structure of ZnO/zeolite

Efek Temperatur dan Waktu Terhadap Total Kandungan Antioksida Dari 5 Jenis Tanaman Herbal dengan Metode Phenanthroline Termodifikasi

Etriyanto Arman, Y. Yefrida; R. Refinel — Thu, 30 Nov 2023 00:00:00 +0700

This research determines the effect of temperature, maceration time, extract storage time at room temperature and refrigerator temperature of the total antioxidant content in miana leaves (Plectranthus scutellarioides (L.)R. Br), papaya leaves (Carica papaya), rambutan leaves (Nephelium lappaceum), bay leaves (Eugenia polyantha) and green betel leaves (Piper betel L). The determination of total antioxidant content was carried out by modified phenanthroline method. Based on the research data. It was found that the optimum conditions for total antioxidant content in the samples above were at 100^oC with 60 minutes of maceration time and without storage time of the extracted samples before being analyzed. The total antioxidant content of miana leaves, papaya leaves, rambutan leaves, bay leaves, and green betel leaves analyzed in the optimum conditions are 3.0865; 1.1554; 0.4641; 0.6764; and 3.3630 mmol Fe/g DW, respectively.