Flavonoid, Phenolic and Antioxidant Content in Several Parts of the Artemisia Plant
DOI:
https://doi.org/10.25077/jku.14.1.24-28.2025Keywords:
antioxidants, artemisia, fenolik, flavonoidAbstract
Free radicals can cause damage to cells in the body. This can be prevented or treated by using substances that are antioxidants. Artemisia plants (Asteraceae family) are one of the potential sources of natural antioxidants. This study was conducted to determine the content and correlation of flavonoids, phenolics and antioxidant activity of leaves, stems and roots of four types of Artemisia genus plants. The method used for the determination of total flavonoid content was the AlCl3 method and the Folin-Ciocalteau method for the determination of total phenolic content. Antioxidant activity was determined by DPPH methods. Based on this study, with the exception of Artemisia vulgaris plants, the antioxidant activity was determined by DPPH and MPM methods., which had the highest quantity in the roots, the leaves contained the highest levels of flavonoids and total phenolics relative to other sections. The data obtained were further tested with ANOVA which showed a significant difference between flavonoid content, phenolic content, and antioxidant activity with plant type and plant part.
References
Pandey, S. K., Anand, U., Siddiqui, W. A. & Tripathi, R., Drug Development Strategies for Malaria: With the Hope for New Antimalarial Drug Discovery—An Update. Adv. Med., 2023: 1–10 (2023).
Alven, S. & Aderibigbe, B. A., Nanoparticles formulations of artemisinin and derivatives as potential therapeutics for the treatment of cancer, leishmaniasis and Malaria. Pharmaceutics, 12(8): 1–34 (2020).
Devkota, H. P. & Aftab, T., Medicinal Plants of the Asteraceae Family: Traditional Uses, Phytochemistry and Pharmacological Activities. Med. Plants Asteraceae Fam. Tradit. Uses, Phytochem. Pharmacol. Act., (December): 1–230 (2022). doi:10.1007/978-981-19-6080-2
Yoon, J. & Kim, M., In vitro evaluation of antidiabetic, antidementia, and antioxidant activity of Artemisia capillaris fermented by Leuconostoc spp. Lwt, 172(October): 114163 (2022).
Budiana, W., Suhardiman, A., Roni, A., Sumarah, I. & Nara, T. E., Kandungan antioksidan ekstrak daun tiga genus Artemisia sp dengan metode DPPH serta penetapan kadar total flavonoid, fenol dan karotenoid. Kartika J. Ilm. Farm., 5(2): 38 (2017).
Pratap-singh, A., Activity of White Wormwood ( Artemisia herba-alba ). 1–13 (2021).
Suriyaprom, S., Srisai, P., Intachaisri, V., Kaewkod, T., Pekkoh, J., Desvaux, M. & Tragoolpua, Y., ( Morus alba L .) Leaf Extracts. (2023).
Shinyuy, L. M., Loe, G. E., Jansen, O., Mamede, L., Ledoux, A., Noukimi, S. F., Abenwie, S. N., et al., Secondary Metabolites Isolated from Artemisia afra and Artemisia annua and Their Anti-Malarial, Anti-Inflammatory and Immunomodulating Properties—Pharmacokinetics and Pharmacodynamics: A Review. Metabolites, 13(5): 1–27 (2023).
Chebbac, K., Ouaritini, Z. B., El Moussaoui, A. , Chalkha, M., Lafraxo, S., Bin Jardan, Y.A., Nafidi, H., Bourhia, M., Guemmouh, R., Antimicrobial and Antioxidant Properties of Chemically Analyzed Es-sential Oil of Artemisia annua L. (Asteraceae) Na-tive to Mediterranean Area, Life, 13, 807 (2023)
Tan, B. L., Norhaizan, M. E., Liew, W. P. P. & Rahman, H. S., Antioxidant and oxidative stress: A mutual interplay in age-related diseases. Front. Pharmacol., 9(OCT): 1–28 (2018).
Elmitra. & Ramadhani, N., Formulasi Obat Kumur Dari Daun Asam Jawa ( Tamarindus indica L .) Dengan Metode Infundasi Mouthwash Formulations Of Leaf Tamarind ( Tamarindus indica L .) With Infundation Method. Borneo J. Pharmascientech, 01(02): 11 (2017).
Yefrida, Y., Suyani, H., Aziz, H. & Efdi, M., Validasi Metode MPM untuk Penentuan Kandungan Antioksidan dalam Sampel Herbal serta Perbandingannya dengan Metode PM, FRAP dan DPPH. J. Ris. Kim., 11(1): 24–34 (2020).
Pandey, B. P., Thapa, R. & Upreti, A., Chemical composition, antioxidant and antibacterial activities of essential oil and methanol extract of Artemisia vulgaris and Gaultheria fragrantissima collected from Nepal. Asian Pac. J. Trop. Med., 10(10): 952–959 (2017).
Ranjbar, M., Naghavi, M. R. & Alizadeh, H., Chemical composition of the essential oils of Artemisia species from Iran: a comparative study using multivariate statistical analysis. J. Essent. Oil Res., 32(4): 361–371 (2020).
Rajabian, A., Khayyat, M. H., Emami, S. A., Tayarani-Najaran, Z., Oskooie, R. R. & Asili, J., Phytochemical evaluation and antioxidant activity of essential oil, and aqueous and organic extracts of Artemisia dracunculus. Jundishapur J. Nat. Pharm. Prod., 12(1): (2017).
Güneş, A., Kordali, Ş., Turan, M. & Usanmaz Bozhüyük, A., Determination of antioxidant enzyme activity and phenolic contents of some species of the Asteraceae family from medicanal plants. Ind. Crops Prod., 137(May): 208–213 (2019).
Yefrida., Suyani, H., Aziz, H. & Efdi, M., Comparison of iron reduction methods on the determination of antioxidants content in vegetables sample. Orient. J. Chem., 34(5): 2418–2424 (2018).
Mumivand, H., Babalar, M., Tabrizi, L., Craker, L. E., Shokrpour, M. & Hadian, J., Antioxidant properties and principal phenolic phytochemicals of Iranian tarragon (Artemisia dracunculus L.) accessions. Hortic. Environ. Biotechnol., 58(4): 414–422 (2017).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Jurnal Kimia Unand

This work is licensed under a Creative Commons Attribution 4.0 International License.
Please find the rights and licenses in Jurnal Kimia Unand (J. Kim. Unand). Authors who publish with J. Kim. Unand agrees to the following policies. No specific document sign-off is required.
1. License
The use of the article will be governed by the Creative Commons Attribution license as currently displayed on the Creative Commons Attribution 4.0 International License.
2. Author(s)' Warranties
The author warrants that the article is original, written by the stated author(s), has not been published before, contains no unlawful statements, does not infringe the rights of others, is subject to copyright that is vested exclusively in the author and free of any third party rights, and that any necessary written permissions to quote from other sources have been obtained by the author(s).
3. User Rights
Under the Creative Commons license, the journal permits users to copy, distribute, and display the material. Users will also need to attribute authors and J. Kim. Unand on distributing works in the journal and other media of publications.
4. Rights of Authors
Authors retain all their rights to the published works, such as (but not limited to) the following rights;
- Copyright and other proprietary rights relating to the article, such as patent rights,
- The right to use the substance of the article in own future works, including lectures and books,
- The right to reproduce the article for own purposes,
- The right to self-archive the article,
- The right to enter into separate, additional contractual arrangements for the non-exclusive distribution of the article's published version (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
5. Co-Authorship
Suppose more than one author jointly prepared the article. In that case, any author submitting the manuscript warrants that he/she has been authorized by all co-authors to be agreed on this copyright and license notice (agreement) on their behalf; and agrees to inform his/her co-authors of the terms of this policy. J. Kim. Unand will not be held liable for anything arising due to the author(s) internal dispute. J. Kim. Unand will only communicate with the corresponding author.
6. Royalties
By submitting the articles, the authors agreed that no fees are payable from J. Kim. Unand.
7. Privacy Statement
The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.
However, due to the advancement and availability of hacking and data mining techniques found over the Internet, J. Kim. Unand cannot guarantee that other parties will not mine our users' email addresses in any possible ways found over the Internet.
8. Miscellaneous
J. Kim. Unand will publish the article (or have it published) in the journal if the article’s editorial process is completed and J. Kim. Unand has become obligated to have the article published. The author acknowledges that the article may be published so that it will be publicly accessible, and such access will be free of charge for the readers.








